Jesse & Joy big winners at Latin Grammy Awards (VIDEO)

Let the world’s love affair with Jesse & Joy begin.

The brother-and-sister folk-pop-rock duo is no secret in their native Mexico, and after Thursday night’s Latin Grammy Awards, the rest of us are taking notice.

They won four Grammy Awards on Thursday night at Mandalay Bay Events Center in Las Vegas, including record and song of the year for “Run!”

“Thanks to people like Juanes and Juan Luis Guerro who have inspired us. Love and peace,” Jesse said.

Also picking up multiple awards were Juanes, Carla Morrison, Don Omar, and Arturo Sandoval, who won two each.

The night’s darlings – Jesse and Joy Huerta, to be official – garnered attention in 2001 as teenagers with “You Got You.”

That led to a recording contract with Warner Music and a 2006 debut album “This is my Life.”

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From there they won Best New Artist a year later. Their most recent album – “Who Gets the Dog? – went platinum in Mexico after spending several weeks at number 1.

Their other awards this year were best contemporary pop vocal album and best video (short form) for “I Leave.”

Juanes’s MTV Unplugged took album of the year and 3BallMTY won best new artist.

A full list of the winners can be found here. 

Also at the Grammys on Thursday, Latin rock pioneer Carlos Santana and Colombian superstar Juanes performed “Look Carefully,” the title track from Juanes’ debut album.

Juanes took home two awards, bringing his career total to 19 and tying Calle 13 for most Latin Grammy awards in history.

They handed out 30 awards before the main telecast on Univision.

Among the notables were Peruvian singer Gian Marco Zignago and Cuban jazz musician Arturo Sandoval.

Zignago won best singer/songwriter album for “20 Years,” while Sandoval won best Latin jazz album (“Dear Diz, Every Day I Think of You”) and best tango album (“Tango, How I Feel You”).

“This is dedicated to my family, children and everyone else,” an emotional Zignago said. “This album is for all the university students from my country to let them know that there are no limits.”